What are the sentinel nodes and what is their role in diagnosis and treatment Cancer? In medical terms, the sentinel node can be defined as the first lymph node (Lymph nodes are the most important part of the immune system) with which the will encounter tumor cells when they try to spread through lymph. Its importance lies in that if the testing sentinel node, not the presence of tumor cells is detected can be ruled out that have spread to glanglios underarm.
SLN in breast cancer
The sentinel node technique is a diagnostic method for identify the axillary node drawing on the breast. If this node is affected, it will be necessary to conduct a study of the rest of the nodes in the armpit. If you are not affected (GC negative without tumor cell invasion) will not have to apply the lymphadenectomy. The role of sentinel node, and there may be more than one, in the diagnosis and treatment of cancer can go much further, as experts have noted, and indeed have opened up new and interesting avenues of research. The sentinel node response is especially important to know the stage when the tumor is breast and melanoma (Skin tumor).
According to the National Cancer Institute US, the sentinel is much more than a ganglion, since being the one located closest to the tumor is the first alert that something is not right. If the lymph nodes in the body detects a foreign substance, its cells are activated and cause a reaction immune system. The response issued by the Sentinel has sponsored exciting advances and new techniques to improve treatment of disease, particularly in its early stages. Thus, for example, to decipher the answer sentinel node prevents emptying of lymphatic armpit region, a more aggressive technique that can cause problems with mobility and arm pain.
SLN in melanoma
The sentinel node reveals whether there has been a spread of melanoma detected. It is essential to determine the stage at which the tumor is and to predict their development, being able to anticipate when establishing the type of treatment. The sentinel node in melanoma to determine if the presence of cells in the skin near the tumor lymph nodes. The sentinel node, as we have seen, to be the first in the chain of nodes on the primary tumor draining alert you if cells have spread.
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